INTRODUCTION: Dermatoglyphics is a branch of genetics that involves the study of ridge patterns in the skin. The skin ridge system and teeth develop from the same embryonic layer during embryogenesis usually around the sixth week.The details of these ridges are permanent. Correlation between dermatoglyphics and dental caries is rationalized due to its similarity to the environment and genetic factors.This cross-sectional study was executed to interpret the association of thumbprint patterns and dental caries. AIM: This study aims to evaluate the association of dermatoglyphics as a genetic predictor of the susceptibility of participants to acquire dental caries using Decayed, Missing and Filled Permanent Scores. MATERIALS AND METHOD: The thumbprint pattern of the right hand was recorded for assessment using the Ink Method. The thumb was rolled on the ink pad and the side of the finger bulb was placed upon an A4 size white sheet paper and rolled to the other side until it faced the opposite direction. For each subject, the DMFT index was calculated according to the number of decayed, missing, and filled permanent teeth using no.23 explorer. RESULTS: Results showed loop pattern had highest DMFT score followed by whorl pattern and arch pattern. STATISTICAL ANALYSIS: The data was analysed using IBM SPSS version 21 (SPSS version 21.0; IBM corporation, Armonk, NY, USA) statistical software. Statistical significance was set at 0.05 levels. Test of normality distribution was found to be p-value<0.05. Intergroup comparison was analysed using F-ANOVA test. The intragroup comparison was analysed using Chi-square test. CONCLUSION: It can be concluded from this study that specific fingerprint patterns may be used as a potentially noninvasive anatomical tool which could be used for screening for dental caries and for guiding future research.