Menstruation and menopause represent pivotal stages in a woman's reproductive life, influencing her body and fertility. This global issue impacts women across diverse backgrounds, with symptoms-induced stress posing risks to cardiovascular health, hormonal balance, and mental well-being. This study explores the comparison of the onset and cessation of the reproductive life span, examining menstrual-related issues, and gynecological problems using questionnaires. The study revealed increase in stress-related symptoms across reproductive phases. At menarche, 64.7% of participants reported anxiety or tension, while this figure rose to 69.8% during the reproductive phase. Similarly, depressive symptoms increased from 52.9% at menarche to 67.4% during the reproductive years. Menopause is marked by a high prevalence of psychological distress, with 88.9% of women experiencing anxiety or nervousness and 94.4% reporting feelings of depression. Additionally, 75% of menopausal women reported hot flashes, and 77.8% experienced sweating.