Low back pain (LBP) is a prevalent and multifaceted health issue affecting women, with significant implications for their overall wellbeing. This review examines the complex interplay of biopsychosocial factors contributing to LBP in women, including biological differences such as spine structure variations and hormonal influences, as well as psychosocial elements like stress and anxiety. Women experience a wide range of symptoms, from localized pain to radiating discomfort and functional impairments, which complicate diagnosis and management. The review highlights that managing LBP requires a combination of non-pharmacological interventions, such as exercise and physical therapy, and careful consideration of pharmacological treatments, including NSAIDs and muscle relaxants, with attention to genderspecific considerations. In severe cases, surgical options may be explored, although their effectiveness varies. The impact of LBP on women's quality of life is profound, leading to functional limitations, psychological distress, and significant economic burdens due to healthcare costs and lost productivity. Preventive strategies are crucial, encompassing lifestyle modifications, ergonomic practices, and public health initiatives aimed at raising awareness and promoting healthy behaviors. The review also identifies future research needs, emphasizing the importance of gender-specific studies and innovative approaches like personalized medicine, telemedicine, and wearable technology. Addressing these areas will be essential for advancing LBP management and improving outcomes for women. Ultimately, this review underscores the necessity for a comprehensive, gender-sensitive approach to tackling LBP to enhance the quality of life and reduce the burden on women's health.