Herbal medicines are widely used nowadays in dentistry and medical practice because of their higher antimicrobial activity, anti-inflammatory properties, biocompatibility and antioxidant properties. Due to ease of accessibility, lesser side effects and beneficial properties, there is an exponential growth of Herbal medicine in medical and dental fields recently. M. oleifera likewise called the "Miracle Tree", is a widely used nourishing food substance that has been discovered beneficial both medicinally and economically, all elements under M. oleifera are considered to be a storehouse of valuable nutrients. Curcuma longa popularly referred to as turmeric is mainly used for its anti-inflammatory properties, it is also used as Oriental medicinal drugs to remedy dental illnesses, including toothache, gastritis, vomiting. Pomegranate (Anar) is another name for Punica Granutam is proven to help control oral infection and microbial counts in periodontitis and fungal infection related to dentures, it is also used as mouth wash popularly in as prophylactic treatment of dental plaque microorganisms. Guava, with its scientific name Psidium guajava, is an excellent antiplaque, antimicrobial, anti-inflammatory, and antioxidant agent used in treating oral diseases. All these Herbal Medicines have remarkable Ethnomedicinal and pharmacological properties, also have a significant role in oral health care. Natural herbs and their formulations are safer, and effective dosage forms can be used for better patient compliance with human beings. This review article highlights the importance of Moringa oleifera, Curcuma longa, Punica Granatam and Psidium guajava on Dentistry and its uses in medicinal fields.