Volume 6 | Issue -14
Volume 6 | Issue -14
Volume 6 | Issue -14
Volume 6 | Issue -14
Volume 6 | Issue -14
The development of a palatable dry powder suspension of Cefetamet Pivoxil Hydrochloride is a safe and effective treatment for upper and lower respiratory tract infections in infants and children. This formulation helps to mask the unpleasant taste and sensitivity to moisture of Cefetamet Pivoxil Hydrochloride(CPH). Creaming index, Sedimentation volume, and flow rate of the reconstituted dry powder suspension were carried out as per the official methods. Various studies were conducted to understand the viscosity and flow behavior of the formulations, and microspheres of Cefetamet Pivoxil Hydrochloride, created using Eudragit E 100, were analyzed. The consistency indices and the flow behaviour index values of the formulations were found to be in the range of 21.72-74.19 and 0.36-0.45 respectively. The study concluded that a palatable Cefetamet Pivoxil Hydrochloride dry powder suspension formulation was successfully developed using sweetening, flavoring, and thickening agents. The optimized formulation, batch F2, complied with the Indian pharmacopoeia limits and exhibited an optimum viscosity for uniform mixing without lumps. Recommended storage between 2-8°C is advised, and the product remains stable at room temperature with a slight increase in viscosity.