Introduction According to a number of descriptions of retrospective analysis about the patient satisfaction level, compared with general anesthesia, the peripheral nerve block has many advantages. Peripheral nerve blocks in upper extremity surgeries improve postoperative pain management and reduce the need for narcotics, as well as the side effects of narcotics such as nausea and vomiting. Interscalene nerve block is performed in shoulder surgeries and lateral end clavicle surgeries. The results of brachial plexus blocks aided by ultrasound are promising and imply that ultrasonic imaging can help in nerve location and direct needle placement. Ropivacaine, a more recent local anesthetic, is an enantiomer of bupivacaine that has fewer neurotoxic and cardiac side effects. As it has no negative side effects, combining ropivacaine and dexmedetomidine in an interscalene block (ISB) results in earlier onset, longer duration, and superior patient satisfaction scores. This study was carried out to evaluate the effect of the combination of ropivacaine and dexmedetomidine for ultrasound-guided (USG) ISB in upper limb orthopedic surgeries in the local population.