Objective: This study aimed to compare the effectiveness of intratympanic (IT) steroid and platelet-rich plasma (PRP) injections in treating patients with sudden sensorineural hearing loss (SSNHL). Methods: A randomized controlled trial was conducted with 60 patients diagnosed with SSNHL within 72 hours of onset. Patients were randomly assigned to receive either a single IT steroid injection (methylprednisolone acetate 40 mg/mL) or a single IT PRP injection (prepared from the patient's own blood). The primary outcome was the change in pure-tone average (PTA) at 4 weeks post-treatment. Secondary outcomes included tinnitus handicap inventory (THI) score. Results: Both treatment groups showed significant improvement in PTA at 4 weeks (p < 0.001). However, there was no statistically significant difference in PTA improvement between the IT steroid and IT PRP groups (p = 0.35). Similarly, no significant differences were found in THI scores between the groups. Conclusion: Both IT steroid and IT PRP injections appear to be effective treatments for SSNHL, with no significant difference in efficacy observed between the two therapies in this study.