To assess the impact of the effectiveness Psychiatry Trigger Tool (PSYTT) in patients suffering from mental health complications Methodology A PSYTT was developed in five stages including literature review, Expert panel screening, Delphi panel review, computing average mean and statistical reliability test, and the final list of triggers. A prospective observational pilot study was performed over two 6-week cycles in a tertiary care teaching hospital. Data was collected using a developed Google form with PSYTT including 59 triggers across five modules viz., Behavioral, clinical, medication, laboratory, and general module. Statistical analysis was performed using SPSS version 21. Results A total of 92 case records were reviewed using the developed tool for 3 months. The triggers were investigated for their presence, frequency, and ability to detect adverse effects. Only 63 case reports had 219 triggers, while 29 cases had no triggers at all. 14 of the 59 PSYTT triggers were identified more than five times in the reviewed cases. Adverse effects were found in 41% of the cases studied. It has been observed that triggers such as somnolence, constipation, extrapyramidal symptoms, tachycardia, and tremor were able to help to identify the adverse effects frequently. Conclusion A set of triggers was specifically designed, developed and validated for detecting ADRs in the psychiatry department. This newly developed PSYTT can assist in ADR detection allowing timely interventions and enhancing safety for patients visiting the psychiatry department. But further research is recommended to explore the applicability of PSYTT in other mental health settings worldwide.