A thorough examination of Chitosan, a direct starch polymer composed of randomly circulated β-(1-4) linked D-glucosamine (a de-acetylated unit) and N-acetyl-Dglucosamine (acetylated units), is presented in this work. Rouget drew it first in 1859, and Hoppe-Seyler gave it an official name in 1894. This cationic polysaccharide has unalienable pharmacological capabilities and is low immunogenic, biocompatible, biodegradable, and effectively accessible. It is also non-lethal. As a result, it is receiving more attention for use in biological and pharmacological applications. Deacetylated chitin, a polysaccharide present in the exoskeleton of shellfish including prawns, lobster and crabs as well as the cell mass of parasites, is what is known as chitosan. After demineralizing the ground exoskeleton with 1% HCl, the exoskeleton is deacetylated with 1⁄2 NaOH to yield chitosan, and finally,After demineralizing the ground exoskeleton with 1% HCl, the exoskeleton is subsequently extracted by dissolving the chitosan in acidic corrosive and reprecipitating it with a pH shift. Chitosan is obtained by deacetylation with 1/2 NaOH. Commercially available CS is 66–95% deacetylated and has a typical atomic weight of between 3800 and 20,000 Daltons. The payback for CS on the amine bunches is approximately 6.5. At neutral pH, it is insoluble, but at acidic pH, it becomes soluble when the chitosan's amino group prorogates and becomes noticeably charged. Through quaternization, the solubility of chitosan in neutral and basic pH can be increased. The atomic weight and degree of organic matter in chitosan have a significant influence on its physicochemical and organic properties. The atomic weight and degree of deacetylation of chitosan have a significant influence on its physicochemical and organic properties. The quantity of protonatable amine groups determines the degree of deacetylation, which in turn determines the polymer's hydrophobicity, solubility, and ability to interact electrostatically with polyanions. The subatomic weight is also very important. Generally speaking, chitosan with lower subatomic weights and deacetylation levels exhibits more notable dissolvability and quicker debasement than its counterparts with higher subatomic weights.