This study investigates the preparation and assessment of a film-forming gel for the topical administration of the antifungal medication griseofulvin over an extended period of time. Improved drug concentration, extended resistance time, and a decrease in side effects such redness, skin irritation, dryness, oedema, and skin peeling are all provided by film-forming gel-based drug delivery systems. The goal of the current study is to create a griseofulvin dosage form that is in the form of a “film forming gel,” eliminating the need for frequent reapplication. Leaves a thin, clear layer on skin after application. Stay on the afflicted area longer and resist being removed by the patient’s clothing.Using design expert software and the three-quarter full factorial design method, an experimental design was created that may provide a sustained release action by achieving the ideal concentrations of carbopol 940 and euragit RS 100 for viscosity and diffusion. For every test, every formulation produced results that fell within an acceptable range. Drug release from the improved formulation was 99.05%. It is possible that this formulation will shorten the course of treatment, gain greater patient acceptance, and represent a breakthrough in the management of fungal skin infections.