ISSN : 2663-2187

LONG EXPOSURE HORMONAL CONTRACEPTIVE HAS POTENTIAL RISK OF BREAST CANCER: A SYSTEMATIC REVIEW

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Lina Nurul Izza, Fanni Hanifa2, Novalia Kridayanti, Retno Sugesti, Husnul Khotimah, Kusworini Handono
ยป doi: 10.33472/AFJBS.6.13.2024.3871-3883

Abstract

Background: Every year there is a rise in the incidence of breast cancer (BC). Age before menopause, family history, obesity, and the use of hormonal products are the causes of breast cancer. One of the things that women require in order to manage birth is hormonal contraception (HC). This article wants to analyze the extent to which the use of hormonal contraceptives is a risk factor for breast cancer. Materials and Methods: Online databases Pubmed, ScienceDirect, Embase, and Crossref were searched for literature research for this investigation. Only open-access publications published between 2014 and 2024 are included in this systematic review.This study incorporates the original paper, which examined the impact of hormonal contraceptive methods on breast cancer in either long-term users or those with a history of usage. Result: PRISMA chart screening turned up 23 articles. These publications mostly demonstrate that using HC increases the risk of BC. A longer history of using hormonal contraceptives is usually linked to a higher risk of developing breast cancer. Conclusion: Hormonal imbalances caused by prolonged exposure to exogenous hormones, like those found in HC, can result in BC. To reduce the risk of BC and other dangers, it is recommended to employ a mix of contraceptive techniques, such as non-hormonal contraception in addition to HC alone.

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