The groundwater quality of a part of Imphal East District of Manipur Valley has been assessed to determine its suitability for drinking and domestic purposes. Thirty four (34) groundwater samples were collected for pre-monsoon (PRM) and post-monsoon (POM) seasons during 2019-2020 and analysed for physico-chemical parameters like temperature (T), pH, electrical conductivity (EC), turbidity (Turb), dissolved oxygen (DO), phosphate (PO4 3- ), nitrate (NO3 - ), total hardness (TH), chloride (Cl- ), total dissolved solids (TDS), total alkalinity (TA), calcium (Ca2+), and magnesium (Mg2+). Analysis results were compared with the WHO (2004) guideline for drinking water. Seasonal variation of parameters is observed in the study area. The physico-chemical parameters like pH, EC, Cl- , Ca2+, Mg2+, TH, and NO3 - were well within the WHO guideline values for drinking water except pH in 2.94% (1), EC in 2.94% (1) PRM & 5.88 % (2) POM, Clin 5.88% (2) samples. Whereas parameters like Turbidity (Turb) in 26.47% (9) PRM and 23.53% (8) POM, PO4 3- in 23 (67.64%) PRM and 19 (55.88%) POM, TDS in 22 (64.70%) samples and TA in all samples (34) exceed the WHO limit. This study reveals that the overall groundwater quality of the study area is not fairly good, being contaminated with turbidity, PO4 3- , TDS, TA, but can be used for drinking and domestic purposes after proper treatment. Present study recommends for regular water quality monitoring and surveillance, encourage water harvesting practice, use of surface water for drinking after proper treatment such as chlorination, defluoridation and desalination.