Introduction: Among noncommunicable diseases, diabetes is one of the major causes of avoidable death and morbidity worldwide. QoL is a measure of an individual's perceived quality of life. Methodology: This cross-sectional study involved 300 individuals with type 2 diabetes who resided in the Sarpara, Kochpara, and Shantipur villages of Kamrup, Assam. The data were collected between January and March 2024. Results: The mean total QOL was 63.70 ± 15.26. At the domain level, 53.7% of the participants had good physical QoL, 13.7% had poor physical QoL, 55% had good psychological QoL, 13.7% had poor psychological QoL, 67.7% had good social QoL, 1% had poor social QoL, 46.3% had good environmental QoL, and 22.4% had poor environmental QoL. Conclusion: Diabetes significantly impacts the multifaceted perception of quality of life (QOL), which includes concerns about the future, emotional stability, physical and role functioning, and social interactions.