Obesity is pertinent to a proinflammatory state, which contributes to chronic inflammation and oxidative stress, both of which lead to the onset of obesity-related problems. An imbalance in the oxidant-antioxidant systems favoring prooxidants results in oxidative stress, which may be detected by monitoring several indicators. The purpose of this study is to assess oxidant and antioxidant levels in obese subjects. This Case-Control research included 45 apparently healthy people and 41 non-obese apparently healthy adults over the age of 18 who were attending the Endocrinology and Metabolism department. Overnight fasting plasma samples were taken in order to test Serum oxidant and antioxidant levels. Serum malondialdehyde and protein carbonyl content levels in the obese group were significantly greater than in the non-obese group (p<0.001). Furthermore, the obese group's mean levels of the antioxidant indicators FRAP and protein thiols were considerably lower than the non-obese group (p0.001). The connection of BMI indicated a significant positive correlation with MDA and PCC and a negative correlation with antioxidant variables FRAP and protein thiols. The occurrence of greater MDA and protein carbonyl levels in obese patients in the current study indicates increased oxidative stress, according to our findings. Furthermore, obese persons have a poor antioxidant state, as seen by low antioxidant indicators FRAP and thiols.