Volume 6 | Issue -14
Volume 6 | Issue -14
Volume 6 | Issue -14
Volume 6 | Issue -14
Volume 6 | Issue -14
Ferulic acid converted into acetyl ferulic acid by treating with acetic anhydride in pyridine and subsequently acetyl feruloyl chloride was prepared using thionyl chloride. Substituted 2-aminothiophenes (1-12) were condensed with acetyl feruloyl chloride to get novel 4-acetoxy-3-methoxy phenyl acrylamide derivatives containing substituted 2-aminothiophenes. All the resulted compounds were deprotected using pyrrolidine to get another set of novel 4-hydroxy-3-methoxy phenyl acrylamide derivatives containing substituted 2-aminothiophenes (1A– 12A). The structures of the title compounds were confirmed based on functional groups, number of protons, number of carbons and molecular weight from FT-IR, 1H-NMR, 13C-NMR and mass spectra respectively.