The Indonesian National Army (TNI) is a state defense tool to uphold the sovereignty of the state, maintain the integrity of the territory and protect the entire nation and all Indonesian blood spills from threats and disturbances to the integrity of the nation and state. To be able to carry out these main tasks, the TNI is required to have good performance. Organizational development, organizational culture and resource quality are important factors needed to improve TNI organizational performance. This study aims to determine the effect of organizational development, organizational culture and quality of human resources on performance. The population in this study were personnel (soldiers and civil servants) who served at TNI Headquarters. The research sample amounted to 105 people with the calculation of the Slovin formula . The research method used is quantitative. Data processing using Structural Equation Model (SEM) with Smart PLS software version 3.3.3. The results showed that: 1) Organizational development has a positive and significant effect on performance. 2) Organizational culture has a positive and significant effect on performance. 3) The quality of human resources has a positive and significant effect on performance. 4) Organizational development has a positive and insignificant effect on the quality of human resources. 5) Organizational culture has a positive and significant effect on the quality of human resources. 6) Organizational development has a positive and insignificant effect on performance mediated by the quality of human resources. 7) Organizational culture has a positive and significant effect on performance mediated by the quality of human resources. 8) The best relationship model to improve performance is through organizational culture on performance with mediation of human resource quality. The implications of this research can be a reference in formulating strategic policies to improve the performance of TNI soldiers through organizational development, organizational culture, and the quality of human resources within the TNI.